检索范围:
排序: 展示方式:
The main and added effects of heat on mortality in 33 Chinese cities from 2007 to 2013
《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1681-5
● The main and added effect from heat co-existed in China.
关键词: Heat Main effect Added effect Mortality Vulnerable population
Molecular mechanisms and therapeutic strategies of vulnerable atherosclerotic plaques
Wen-Qiang CHEN MD, Yun ZHANG MD, PhD, FACC,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 36-42 doi: 10.1007/s11684-010-0020-y
关键词: vulnerable plaque animal models mechani-sm detection treatment
Simulation of bubble column reactors using CFD coupled with a population balance model
Tiefeng WANG
《化学科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 162-172 doi: 10.1007/s11705-009-0267-5
关键词: bubble column computational fluid dynamics bubble breakup and coalescence population balance model bubble size distribution
Hongyan LI, Yu ZHANG, Min YANG, Yoichi KAMAGATA
《环境科学与工程前沿(英文)》 2013年 第7卷 第1期 页码 43-48 doi: 10.1007/s11783-012-0397-8
关键词: ammonia-oxidizing bacteria hydraulic retention time nitrification activity nitrite-oxidizing bacteria population dynamics
Socialized care services for the aged population: System construction and support measures
《工程管理前沿(英文)》 2023年 第10卷 第2期 页码 339-353 doi: 10.1007/s42524-022-0208-2
关键词: socialized care service for the elderly system construction support measure
null
《医学前沿(英文)》 2012年 第6卷 第3期 页码 322-328 doi: 10.1007/s11684-012-0204-8
The aim of this study was to determine the prevalence of overweight and obese subjects in the Shanghai population of China and its association with undiagnosed hypertension, by taking age, gender and place of residence (urban or suburban) into account. A cross-sectional population-based survey was conducted in 2007. The sample included 13 359 participants aged 15–69 years. Weight, height, and blood pressure were recorded, and information about gender, age and place of residence was obtained. Overweight and obesity prevalence were calculated by the body mass index (BMI) definition recommended by Working Group on Obesity in China (normal weight, 18.5–23.9 kg/m2; overweight, 24–27.9 kg/m2; obesity,≥28 kg/m2). Undiagnosed hypertension was defined by China criteria in accord with that of WHO-ISH (subjects with systolic pressure≥140 mmHg, and/or diastolic pressure≥90 mmHg). Multiple logistic regression analyses were used to assess the association of overweight or obesity with undiagnosed hypertension by adjusting for age, gender and place of residence. The overall overweight, obesity, and undiagnosed hypertension prevalence were 27.6% (95% CI: 26.8–28.4), 6.6% (95% CI: 6.2–7.0), and 15.5% (95% CI: 14.9–16.1), respectively. Compared to normal weight subjects, the odds ratios (OR) for subjects who were overweight and had hypertension was 2.33 (95% CI: 2.10–2.59); that for obesity and hypertension was 4.27 (95% CI: 3.66–4.99). These data suggest that overweight and obesity prevalence and their association with undiagnosed hypertension are high in our study population.
关键词: overweight obesity undiagnosed hypertension prevalence association
Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era
null
《医学前沿(英文)》 2012年 第6卷 第2期 页码 204-211 doi: 10.1007/s11684-012-0202-x
We evaluated the outcomes of chronic myeloid leukemia (CML) patients in three clinical phases, namely, chronic (CP), accelerated (AP), and blast (BP) phases, receiving imatinib treatment. The single-institution treatment experiences of Chinese patients with CML were presented. A total of 275 CML patients (CP, 210; AP, 24; and BP, 41) who received imatinib between February 2001 and April 2008 were enrolled in this study. We evaluated the responses (hematologic, cytogenetic, and molecular), overall survival (OS), treatment event-free survival (EFS), and prognostic factors of outcome. At the cut-off point, the complete cytogenetic response (CCyR) and complete molecular response rates of patients in the CP were 84.7% and 61.9%, respectively, which were significantly higher than those of patients in the AP (50% and 29.1%, respectively, both P<0.001) and BP (24.3% and 9.7%, respectively, both P<0.001). The estimated five-year OS and five-year EFS rates were 93.2% and 86.4% for CP patients, as well as 64.5% and 50.9% for AP patients, which were significantly higher than those for BP patients (P<0.001). In CP patients, univariate analysis revealed that early treatment with imatinib, achieving CCyR within 12 months, additional cytogenetic abnormalities, and kinase domain mutations were associated with the treatment outcome. More patients are needed to carry out multivariate analysis.
关键词: imatinib chronic myeloid leukemia complete cytogenetic response
Projections of heat-related excess mortality in China due to climate change, population and aging
《环境科学与工程前沿(英文)》 2023年 第17卷 第11期 doi: 10.1007/s11783-023-1732-y
● Four scenarios were used to project heat-related excess mortality in China.
Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han
《医学前沿(英文)》 页码 185-192 doi: 10.1007/s11684-020-0754-0
It has been known that, the novel coronavirus, 2019-nCoV, which is considered similar to SARS-CoV and originated from Wuhan (China), invades human cells via the receptor angiotensin converting enzyme II (ACE2). Moreover, lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infection. However, some patients also exhibit non-respiratory symptoms, such as kidney failure, implying that 2019-nCoV could also invade other organs. To construct a risk map of different human organs, we analyzed the single-cell RNA sequencing (scRNA-seq) datasets derived from major human physiological systems, including the respiratory, cardiovascular, digestive, and urinary systems. Through scRNA-seq data analyses, we identified the organs at risk, such as lung, heart, esophagus, kidney, bladder, and ileum, and located specific cell types (i.e., type II alveolar cells (AT2), myocardial cells, proximal tubule cells of the kidney, ileum and esophagus epithelial cells, and bladder urothelial cells), which are vulnerable to 2019-nCoV infection. Based on the findings, we constructed a risk map indicating the vulnerability of different organs to 2019-nCoV infection. This study may provide potential clues for further investigation of the pathogenesis and route of 2019-nCoV infection.
Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern
null
《医学前沿(英文)》 2014年 第8卷 第1期 页码 113-117 doi: 10.1007/s11684-014-0310-x
Papillary thyroid carcinoma (PTC) is one of the most common tumors of the thyroid gland. The common risk factors of PTC include ionizing radiation, positive family history, and thyroid nodular disease. PTC was identified in Europeans by conducting a genome-wide association study, and a strong association signal with PTC was observed in rs944289 and NKX2-1 (located at the 14q13.3 locus), which was probably the genetic risk factor of PTC. This study aimed to examine the association of this gene with PTC in Chinese. A total of 354 patients with PTC and 360 healthy control subjects from the Han population of Northern China were recruited in the study. These individuals were genotyped to determine rs12589672, rs12894724, rs2076751, and rs944289. The association of rs944289 with PTC was obtained (C vs. T, P=0.027, OR=1.264, 95% CI=1.026-1.557; and C/C-C/T vs. T/T, P=0.034, OR=1.474, 95% CI=1.028-2.112). Conducting a subgroup analysis, we found a marginal difference in the allele frequency distribution of rs944289 (adjusted P=0.062) between the patients with PTC and multi-nodular goiter and the control subjects. We also observed an interaction (P=0.029; OR=2.578, 95% CI=1.104-6.023) between rs944289 and diabetes in patients with PTC. In conclusion, rs944289 was associated with an increased risk of PTC in the Han population of Northern China, but no clear association was observed in either of the tag single nucleotide polymorphisms of NKX2-1.
关键词:
Genetic diversity and population structure of indigenous chicken breeds in South China
Xunhe HUANG,Jinfeng ZHANG,Danlin HE,Xiquan ZHANG,Fusheng ZHONG,Weina LI,Qingmei ZHENG,Jiebo CHEN,Bingwang DU
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 97-101 doi: 10.15302/J-FASE-2016102
关键词: microsatellites genetic diversity population structure indigenous chicken South China conservation
《医学前沿(英文)》 2021年 第15卷 第6期 页码 903-912 doi: 10.1007/s11684-021-0871-4
关键词: homocysteine hyperhomocysteinemia H-type hypertension Chinese
《环境科学与工程前沿(英文)》 2022年 第16卷 第8期 doi: 10.1007/s11783-022-1522-y
• Simultaneous C & N removal in Methammox occurs at wide C:N ratio.
关键词: Methanogens Biological Nitrogen Removal (BNR) Simultaneous Methammox C:N ratio
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
《环境科学与工程前沿(英文)》 2011年 第5卷 第1期 页码 48-56 doi: 10.1007/s11783-011-0305-7
关键词: ammonium-rich wastewater membrane biofilm reactor nitrification redox stratification shortcut nitrogen removal
《环境科学与工程前沿(英文)》 2022年 第16卷 第9期 doi: 10.1007/s11783-022-1552-5
• The airborne bacteria of Mexico City are representative of urban environments.
关键词: Airborne bacteria Urbanisation PM10 Mexico City Microbiome
标题 作者 时间 类型 操作
Molecular mechanisms and therapeutic strategies of vulnerable atherosclerotic plaques
Wen-Qiang CHEN MD, Yun ZHANG MD, PhD, FACC,
期刊论文
Simulation of bubble column reactors using CFD coupled with a population balance model
Tiefeng WANG
期刊论文
Effects of hydraulic retention time on nitrification activities and population dynamics of a conventional
Hongyan LI, Yu ZHANG, Min YANG, Yoichi KAMAGATA
期刊论文
Obesity and overweight prevalence and its association with undiagnosed hypertension in Shanghai population, China: a cross-sectional population-based survey
null
期刊论文
Projections of heat-related excess mortality in China due to climate change, population and aging
期刊论文
data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable
Xin Zou, Ke Chen, Jiawei Zou, Peiyi Han, Jie Hao, Zeguang Han
期刊论文
Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern
null
期刊论文
Genetic diversity and population structure of indigenous chicken breeds in South China
Xunhe HUANG,Jinfeng ZHANG,Danlin HE,Xiquan ZHANG,Fusheng ZHONG,Weina LI,Qingmei ZHENG,Jiebo CHEN,Bingwang DU
期刊论文
Status of hyperhomocysteinemia in China: results from the China Stroke High-risk Population Screening
期刊论文
Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:
期刊论文
Nitrifying population dynamics in a redox stratified membrane biofilm reactor (RSMBR) for treating ammonium-rich
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
期刊论文